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Funding · State

Top 277 Massachusetts startups by funding raised

277 companies headquartered in Massachusetts disclosed $21.4B across 358 SEC Form D offerings of $20M or more between Q3 2021 and Q2 2026.

$21.4B
Total disclosed
277
Companies
358
Offerings
-17%
Latest year vs the year before

Most funded in Massachusetts

By total disclosed across the period, one row per company. Combine filters to narrow — "Recently funded" plus "Hiring now" is who just raised and is actively recruiting.

$671M
$669M
Nexamp, Inc. nexamp.com ↗
Energy & Climate · 3 offerings · 38 open roles
$622M
$591M
$525M
Cengage Learning Holdings II, Inc.
$474M
Neumora Therapeutics, Inc.
$389M
$274M
$250M
Starburst Data, Inc.
$241M
$227M
Aura Group, Inc. aura.com ↗
Software & Technology · 2 offerings · 5 open roles
$226M
Seaport Therapeutics, Inc.
$220M
Reify Health, Inc.
$215M
Arbor Biotechnologies, Inc.
$209M
$205M
$200M
Zenas BioPharma, Inc.
$200M
$196M
$189M
$187M
$187M
$175M
$173M
Preply, Inc. preply.com ↗
Software & Technology · 3 offerings · 105 open roles
$172M
$167M
$163M
$160M
$159M
$158M
$157M
$155M
$155M
$145M
$144M
Ambri Inc.
$143M
$140M
$135M
Chroma Medicine, Inc.
$133M
$132M
Saliogen Therapeutics, Inc.
$131M
$130M
$130M
Solo.io, Inc.
$129M
Ensoma, Inc.
$126M
$126M
Scorpion Therapeutics, Inc.
$124M
$123M
$122M
$122M
INSURIFY, INC. insurify.com ↗
Software & Technology · 2 offerings · 15 open roles
$121M
Solstice Oncology, Inc.
$115M
$112M
PepGen Inc.
$111M
$107M
$100M
Dianthus Therapeutics, Inc.
$100M
Acrivon Therapeutics, Inc.
$99M
OPEN BLUE SEA FARMS, INC.
$95M
$94M
CodaMetrix Inc. codametrix.com ↗
Healthcare · 2 offerings · 1 open roles
$93M
Newleos Therapeutics, Inc.
$92M
$91M
$90M
Vigil Neuroscience, Inc.
$90M
$88M
$85M
$85M
TakeOff Technologies, Inc.
$85M
$85M
$83M
Cedilla Therapeutics, Inc.
$82M
Satellite Biosciences, Inc.
$82M
$81M
$80M
Sherlock Biosciences, Inc.
$80M
$77M
$76M
$75M
Avilar Therapeutics, Inc.
$75M
Hydration Labs, Inc.
$75M
ConnectRN, Inc.
$75M
Vecna Robotics, Inc.
$74M
$73M
$73M
$72M
$72M
Well Dot, Inc.
$72M
$70M
Ventus Therapeutics U.S., Inc.
$70M
$70M
$69M
$68M
$67M
Imbria Pharmaceuticals, Inc.
$66M
$66M
$65M
Creatio Inc.
$65M
Stipple Bio, Inc.
$65M
$64M
$62M
Zus Health, Inc. zushealth.com ↗
Healthcare · 2 offerings · 6 open roles
$62M
$61M
$61M
Redona Therapeutics, Inc.
$60M
$60M
QurAlis Corp
$59M
$59M
Corner Therapeutics, Inc.
$58M
$58M
$58M
Accountable Care Transactions, Inc.
$58M
InfoBionic, Inc.
$57M
Emulate, Inc.
$57M
$55M
Invetx, Inc.
$55M
INTRINSIC THERAPEUTICS INC
$55M
THIRD POLE, INC.
$54M
$53M
Bambusa Therapeutics, Inc.
$53M
$53M
$52M
Quaise Energy, Inc.
$51M
$51M
$51M
Ratio Therapeutics, Inc.
$50M
Kelonia Therapeutics, Inc.
$50M
Kula Bio, Inc.
$50M
$50M
Wise Systems, Inc.
$48M
$48M
$46M
$46M
Clade Therapeutics, Inc.
$46M
$45M
1upHealth, Inc.
$45M
Abata Therapeutics, Inc.
$45M
Heartland Water Technology, Inc.
$45M
Spear Bio Inc.
$45M
Ankyra Therapeutics, Inc.
$44M
$44M
Convergent Dental, Inc.
$43M
WiTricity Holdings, Inc.
$43M
SimSpace Corp
$42M
$42M
Botkeeper Inc.
$42M
$42M
Matchpoint Therapeutics Inc.
$41M
Abacus Insights, Inc.
$41M
Skylark Bio, Inc.
$41M
ACTIV Surgical, Inc.
$40M
$40M
Entact Bio, Inc.
$40M
$40M
Lookout, Inc.
$40M
$39M
Windgap Medical, Inc.
$39M
Transition Bio, Inc.
$38M
Teikametrics, Inc.
$38M
Memento Medicines, Inc.
$38M
Carbon Biosciences, Inc.
$38M
Via Separations, Inc
$38M
Lexington Medical, Inc.
$38M
Caldera Therapeutics, Inc.
$37M
$36M
Bicycle Health Inc.
$35M
Cartwheel Care Inc.
$35M
$35M
Coin Metrics Inc.
$35M
$35M
Altaeros Energies, Inc.
$34M
$34M
AXOFT, INC.
$34M
$34M
i2O Therapeutics, Inc.
$34M
Pyramid Biosciences, Inc.
$33M
LineVision, Inc.
$33M
TileDB, Inc.
$33M
$32M
Kytopen Corp.
$32M
SURGE Therapeutics, Inc.
$32M
Anumana, Inc.
$32M
Aliada Therapeutics, Inc.
$32M
Soft Robotics Inc.
$32M
OcuTerra Therapeutics, Inc.
$31M
$31M
Lotus Parent, Inc.
$31M
AcuityMD, Inc.
$31M
Notarize, Inc.
$31M
Novoscribe, Inc.
$31M
Reprieve Cardiovascular, Inc.
$31M
Appcues, Inc.
$31M
Hyalex Orthopaedics, Inc.
$30M
OncXerna Therapeutics, Ltd.
$30M
Uwill, Inc.
$30M
RYNE Biotechnology Inc.
$30M
$30M
$30M
Mythic Therapeutics, Inc.
$30M
Consensus NLP Inc.
$30M
Appex Group, Inc.
$30M
$29M
HYCU Holdings, Inc.
$29M
Alloy Enterprises Inc.
$29M
Pinteon Therapeutics, Inc.
$29M
Centrexion Therapeutics Corp
$29M
Immunitas Therapeutics, Inc.
$29M
SparkCharge, Inc.
$29M
Neuralmagic, Inc.
$29M
Kinaset Therapeutics, Inc.
$28M
Via Science, Inc.
$28M
Boston Materials, Inc.
$28M
Robin Powered, Inc.
$27M
GRO Biosciences Inc.
$27M
AXIAL THERAPEUTICS, INC.
$27M
CardioFocus, Inc.
$27M
Tidelift, Inc.
$27M
Axena Health, Inc.
$26M
CXL OPHTHALMICS, INC.
$26M
Rejoni, Inc.
$26M
$26M
Empatica, Inc.
$26M
Artax Biopharma, Inc.
$26M
Epicore Biosystems, Inc.
$25M
$25M
eGenesis, Inc.
$25M
AVAVA, Inc.
$25M
$25M
Volta Labs, Inc.
$25M
Keystone Dental Holdings, Inc.
$25M
Ribon Therapeutics, Inc.
$25M
Lonestar Medicines, Inc.
$25M
RightHand Robotics, Inc.
$25M
$25M
PERCH ENERGY, INC.
$25M
SYNTIS BIO, INC.
$25M
$25M
Concerto Biosciences, Inc.
$24M
Summation Bio, Inc.
$24M
Sea Street Technologies, Inc.
$24M
MINERVA BIOTECHNOLOGIES Corp
$24M
Myrobalan Therapeutics Holding, Inc.
$24M
Qlaris Bio, Inc.
$24M
Paragonix Technologies, Inc.
$24M
Amplitude Vascular Systems, Inc.
$24M
$23M
NextRNA Therapeutics, Inc.
$23M
NEUTROLIS INC.
$23M
$23M
$23M
$23M
MediSix Therapeutics, Inc.
$22M
Biothea Pharma, Inc.
$22M
NormShield Inc.
$22M
Elicio Therapeutics, Inc.
$22M
$22M
123 See, Inc.
$22M
EnPlusOne Biosciences Inc.
$22M
CyberSaint, Inc.
$21M
Druid AI USA Inc.
$21M
Gather Health Primary Care, Inc.
$21M
$21M
Mobi Systems, Inc.
$21M
RF Ultimate Parent, Inc.
$21M
Paperless Parts, Inc.
$21M
Slim.AI, Inc.
$21M
GT Spirits, Inc.
$21M
Alloplex Biotherapeutics, Inc.
$21M
Access Vascular, Inc.
$20M
BetterVet, Inc.
$20M
March Therapeutics, Inc.
$20M
SecZetta, Inc.
$20M
Kernal Biologics, Inc.
$20M
ClearGov Inc.
$20M
$20M
NFlection Therapeutics, Inc.
$20M
CallMiner, Inc.
$20M

Filter definitions — Hiring now: open roles on the company's public job board as of Sep 5, 2026. Hiring remote: that board lists remote or distributed roles. Recently funded: a Form D filed in the trailing twelve months. $100M+/$500M+: cumulative disclosed amount across all offerings. Repeat raisers: more than one offering on file. Up-and-coming: incorporated within the last four years and recently funded — incorporation year is disclosed by roughly half of filers, so this undercounts.

What Massachusetts funds

$10.9B · 171
$7.49B · 132
$1.51B · 35
$1.14B · 13
$149M · 2
$40M · 2
$21M · 1

Also on startersss

Boston startups (93 funded companies) →Cambridge startups (64 funded companies) →Watertown startups (16 funded companies) →Waltham startups (19 funded companies) → Accelerator programs founders can apply to → How US startup funding has moved over 20 quarters →

Source: SEC Form D structured data. Amounts are self-reported by the issuer on a notice filing — not audited, and cumulative across amendments. Full methodology →