Startup ecosystem

Top startups in Cambridge.

64 Cambridge companies have disclosed $4.34B in SEC filings, and founders there can apply to 16 accelerator programs.

64 funded companies · $4.34B · 16 accelerators · 3 hiring now · Reviewed Jul 2026

Most funded in Cambridge

By total disclosed across the period, one row per company. Combine filters to narrow — "Recently funded" plus "Hiring now" is who just raised and is actively recruiting.

$215M
Arbor Biotechnologies, Inc.
$132M
Saliogen Therapeutics, Inc.
$130M
Solo.io, Inc.
$122M
INSURIFY, INC. insurify.com ↗
Software & Technology · 2 offerings · 17 open roles
$107M
$90M
Vigil Neuroscience, Inc.
$83M
Cedilla Therapeutics, Inc.
$82M
Satellite Biosciences, Inc.
$70M
$65M
Stipple Bio, Inc.
$60M
QurAlis Corp
$52M
Quaise Energy, Inc.
$50M
Kelonia Therapeutics, Inc.
$50M
Wise Systems, Inc.
$46M
Clade Therapeutics, Inc.
$45M
Abata Therapeutics, Inc.
$42M
Matchpoint Therapeutics Inc.
$41M
Skylark Bio, Inc.
$39M
Transition Bio, Inc.
$35M
Cartwheel Care Inc.
$34M
AXOFT, INC.
$34M
i2O Therapeutics, Inc.
$33M
TileDB, Inc.
$32M
Kytopen Corp.
$32M
SURGE Therapeutics, Inc.
$32M
Anumana, Inc.
$30M
RYNE Biotechnology Inc.
$26M
Empatica, Inc.
$26M
Artax Biopharma, Inc.
$26M
Epicore Biosystems, Inc.
$25M
eGenesis, Inc.
$25M
Volta Labs, Inc.
$25M
Ribon Therapeutics, Inc.
$24M
Paragonix Technologies, Inc.
$23M
NextRNA Therapeutics, Inc.
$23M
NEUTROLIS INC.
$21M
Druid AI USA Inc.
$20M
March Therapeutics, Inc.
$20M
Kernal Biologics, Inc.

Filter definitions — Hiring now: open roles on the company's public job board as of Aug 10, 2026. Hiring remote: that board lists remote or distributed roles. Recently funded: a Form D filed in the trailing twelve months. $100M+/$500M+: cumulative disclosed amount across all offerings. Repeat raisers: more than one offering on file. Up-and-coming: incorporated within the last four years and recently funded — incorporation year is disclosed by roughly half of filers, so this undercounts.

Accelerators in Cambridge

Cambridge founders can apply to 16 accelerator programs in our directory — including Accelerate Cambridge, Cogo Labs, Cybersecurity Factory, Deeptech Labs, Downing Enterprise, HubSpot Ventures.

The best accelerators in Cambridge → Accelerators with open applications →