Startup ecosystem
Top startups in Boston.
Boston, anchored by MIT and Harvard, is a global leader in biotech and deep tech, with a deep bench of enterprise-software and life-sciences companies spun out of its research institutions.
Notable startups
A curated list of companies headquartered in Boston, spanning the sectors that define its ecosystem. Each links to the company; where we hold their pitch deck, it's linked too.
Inbound marketing, sales, and CRM platform for growing businesses.
Founded
2006
Stage
Public
Restaurant technology platform combining point-of-sale, payments, and operations software.
Founded
2011
Stage
Public
Marketing automation and customer-data platform built for e-commerce brands.
Founded
2012
Stage
Public
Data-analytics platform built on Trino for querying data across many sources at once.
Founded
2017
Stage
Series D
Valuation
~$3.4B
Enterprise AI platform for building, deploying, and managing machine-learning models.
Founded
2012
Stage
Late Stage
Financial-technology firm and issuer of the USDC stablecoin.
Founded
2013
Stage
Public
Synthetic-biology company engineering microbes and offering cell-programming as a platform.
Founded
2008
Stage
Public
Metal and mass-production 3D-printing company for industrial manufacturing.
Founded
2015
Stage
Public
Desktop and industrial 3D-printer maker democratizing professional-grade fabrication.
Founded
2011
Stage
Late Stage
Valuation
~$2B
Technology-driven Medicare Advantage health plan and care provider for seniors.
Founded
2017
Stage
Late Stage
Valuation
~$12B
Global payments platform specializing in complex, high-value cross-border transactions.
Founded
2011
Stage
Public
Agtech company using microbiology and data to improve crop yields and sustainability.
Founded
2014
Stage
Late Stage
Valuations are approximate, drawn from the most recent reported figures as of Jul 2026.
Accelerators in Boston
Boston founders can apply to 30 accelerator programs in our directory — including AcceliCITY, Accelr8, Air Force Accelerator Powered by Techstars, Boston University Venture Accelerator, CARB-X, Cleantech open Northeast.