Startup ecosystem

Top startups in Irvine.

17 Irvine companies have disclosed $1.48B in SEC filings, and founders there can apply to 3 accelerator programs.

17 funded companies · $1.48B · 3 accelerators · 1 hiring now · Reviewed Jul 2026

Most funded in Irvine

By total disclosed across the period, one row per company. Combine filters to narrow — "Recently funded" plus "Hiring now" is who just raised and is actively recruiting.

$102M
Swift Health Systems Inc.
$100M
JenaValve Technology Inc
$56M
Syntiant Corp.
$39M
Stroma Medical Corp
$38M
$36M
PatientFi, Inc.
$31M
Bright Uro, Inc.
$29M
$25M
Diality Inc
$23M
Telesair, Inc.

Filter definitions — Hiring now: open roles on the company's public job board as of Aug 10, 2026. Hiring remote: that board lists remote or distributed roles. Recently funded: a Form D filed in the trailing twelve months. $100M+/$500M+: cumulative disclosed amount across all offerings. Repeat raisers: more than one offering on file. Up-and-coming: incorporated within the last four years and recently funded — incorporation year is disclosed by roughly half of filers, so this undercounts.

Accelerators in Irvine

Irvine founders can apply to 3 accelerator programs in our directory — including Doordasht Venture, UCI Applied Innovation, Vena Vitals.

The best accelerators in Irvine → Accelerators with open applications →