Startup ecosystem

Top startups in Houston.

27 Houston companies have disclosed $3.23B in SEC filings, and founders there can apply to 7 accelerator programs.

27 funded companies · $3.23B · 7 accelerators · 1 hiring now · Reviewed Jul 2026

Most funded in Houston

By total disclosed across the period, one row per company. Combine filters to narrow — "Recently funded" plus "Hiring now" is who just raised and is actively recruiting.

$357M
Solugen, Inc.
$300M
Vyripharm Enterprises, Inc.
$150M
Lancium Technologies Corp
$148M
$145M
BLOEM LIFE ENTERPRISE, INC.
$75M
NEXT Renewable Fuels, Inc.
$58M
Procyrion, Inc.
$44M
ImmunoGenesis, Inc.
$41M
P97 Holdings, Inc.
$28M
MetOx Technologies, Inc.
$26M
RepeatMD, Inc.
$26M
Innovapptive, Inc.
$25M
SmartAC.com, Inc.
$23M
SunGas Renewables Inc.
$22M
PieTech, Inc.
$22M
March Biosciences, Inc.
$22M
Stream Biomedical, Inc.

Filter definitions — Hiring now: open roles on the company's public job board as of Aug 10, 2026. Hiring remote: that board lists remote or distributed roles. Recently funded: a Form D filed in the trailing twelve months. $100M+/$500M+: cumulative disclosed amount across all offerings. Repeat raisers: more than one offering on file. Up-and-coming: incorporated within the last four years and recently funded — incorporation year is disclosed by roughly half of filers, so this undercounts.